As I’ve explored before, whether young or old, male or female, smoker or non-smoker, with high blood pressure or low-grade blood pressure, high cholesterol or low-pitched, having high levels of a harmful deepen announced TMAO–trimethylamine oxide–in the bloodstream is associated with a significantly higher risk of having a heart attack, stroking, or dying over a three-year period. Where does TMAO come from? As I probe in my video How to Develop a Healthy Gut Ecosystem, the choline in foods like eggs can be turned by intestine bacteria into TMAO, which is then absorbed back into our organisation. And, the more eggs we eat, the higher the levels climb, as “youre seeing” at 0:41 in my video.
Given the similarity in organize between carnitine and choline, Cleveland Clinic researchers wondered if carnitine is located within red meat, force guzzles, and adds-on might also lead to TMAO production and gave it to the test. As you can see at 1:00 in my video, if you feed omnivores, those who regularly devour flesh, a steak, their TMAO positions shoot up. Those who feed rigorously plant-based may start out with almost no TMAO in their organization, presumably because they’re not ingesting any flesh, eggs, or dairy. But, even if vegans gobble a sirloin, still almost no TMAO is shaped. Why? Presumably, they don’t have steak-eating bacteria in their bowels. Definitely, it was found that no TMAO is produced if you don’t have TMAO-producing bacteria in your gut. If you don’t regularly chew meat, then you’re not stimulating the growth of the meat-eating microbes that render TMAO.
This suggests that once we develop a plant-based gut ecosystem, our bacteria will not produce TMAO, even if we eat meat every once and awhile. However, we still don’t know how rapidly gut bacteria shift after a change in our diet–but it does not appear to be all or nothing. If mortals snacking the standard American diet are given two sausage, egg, and cheese cookies before and after just five days of chewing lots of similarly high-fat dinners, their TMAO production enhances even higher, as “youre seeing” at 2:09 in my video. So, it’s not just whether “were having” the bad faults or not. Apparently, we are able to engendered more of them the more we feed them.
Meat-free diets, on the other hand, can also have been “demonstrated to have a profound influence on human rights metabolism.”Just by analysing a urine test, we can tell what kind of diet people eat, based on assessments like how low-toned TMAO levels are in the urine of those dining egg-free vegetarian foods, as you can see at 2:26 in my video. At 2:43 in my video, you’ll see that we can even take the same parties rotate them by using three different nutritions, and calculate who is on a high-meat diet, low-meat diet, or no-meat diet, based in part on the different combinations churned out by the different gut flora or different botany work after just about two weeks on the different nutritions. It’s possible that some of the beneficial effects of whole plant foods may be mediated by the effects they have on our intestine bacteria. At the same time, the standard American diet further increase the relative abundance of unwanteds that make toxic deepens including TMAO( as “youre seeing” at 3:07 in my video ).
Strictly plant-based diets have gained credence as a dietary approach for preventing and succeeding sicknes. Perhaps, in part, this is because of their rather unique gut flora, with less of the disease-causing bacteria and more of the protective species. So, all along, we visualized the reason those munching plant-based had lower coronary thrombosis proportions was because they were dining less saturated fatty and cholesterol, but perhaps their lower TMAO tiers may also be contributing to their benefits, thanks to their reduced ingestion of carnitine and choline.
I talked about the egg industry response to the choline revelation in Egg Industry Response to Choline and TMAO. How has the carnitine supplement industry reacted? In response to the research implicating carnitine in TMAO production, the former vice president of AdvoCare–a multilevel marketing company that sells carnitine supplements like AdvoCare Slam while coming slammed with suits find them guilty of being “engaged in false, misinforming or deceitful plays or practices” and forced to pay more than a million dollars–questioned whether there was a secret vegan conspiracy at the Cleveland Clinic. Restricting our intake of flesh or carnitine supplements to prevent our bowel bacteria from originating TMAO, he argued, is like trying to prevent car accidents by restricting sales of fuel.
Okay…but there are benefits to transportation. We’re talking about TMAO, which may be fueling our epidemic of myocardial infarction, the number-one killer of men and women in this country. As far as I’m concerned, the more we can cut the fuel for that, the better.
For more background on TMAO, picture Carnitine, Choline, Cancer, and Cholesterol: The TMAO Connection, then find out How to Reduce Your TMAO Levels.
Our gut flora are what we eat. Check out 😛 TAGEND
Microbiome: The Inside Story Microbiome: We Are What They Snack Prebiotics: Tending Our Inner Garden What’s Your Gut Microbiome Enterotype ? How to Change Your Enterotype Paleopoo: What We Can Learn from Fossilized Feces Gut Dysbiosis: Starving Our Microbial Self Is Obesity Infectious ?
In health, Michael Greger, M.D.
PS: If you haven’t yet, you can subscribe to my free videos here and watch my live lectures 😛 TAGEND
2019: Evidence-Based Weight Loss 2016: How Not To Die: The Role of Diet in Preventing, Arresting, and Reversing Our Top 15 Killers 2015: Food as Medicine: Preventing and Treating the Most Dreaded Diseases with Diet 2014: From Table to Able: Combating Disabling Diseases with Food 2013: More Than an Apple a Day 2012: Uprooting the Leading Causes of Death
Read more: nutritionfacts.org