What to Eat and Avoid for Women with BRCA Gene Mutations

Wealth Health Self

Five studies have been performed on breast cancer survival and soy foods involving more than 10,000 breast cancer cases, and together they found that those who eat more soy live longer and have a lower peril of the cancer coming back. What about women who carry breast cancer genes? Fewer than 10 percentage of breast cancer actions run in families, but when they do, it tends to be mutants to one of the tumor suppressor genes, BRCA1 or BRCA2. BRCA 1 and BRCA two were involved in DNA repair, so if either one of them is marred, chromosomal irregularities can be generated, which can provided us up for cancer. I examine this in my video Should Women at High Risk for Breast Cancer Avoid Soy ?.

This idea that we have tumor suppressor genes goes back to acclaimed study from the 1960 s that showed that if we fuse together a ordinary cadre with a cancer cell, rather than the cancer cell turning the normal cell malignant, the normal cell actually muffles the cancerous one. Tumor suppressor genes are typically split into two types: gatekeeper genes that retain cancer cadres in check and caretaker genes that foreclose the cadre from becoming cancerous in the first place. BRCA genes loom able to do both, which is why their gathering is so important.

Until recently, dietary recommendations for those with mutants to BRCA genes focused on reducing DNA damages caused by free radicals by eating lots of antioxidant-packed fruits and veggies. If our DNA repair capacity is low, we want to be extra careful about damaging our DNA in the first place. But what if we could also boost BRCA function? In my video BRCA Breast Cancer Genes and Soy, I showed how, in vitro, soy phytoestrogens could turn back on BRCA protection stifled by breast cancer, upregulating BRCA saying as much as 1,000 percentage within 48 hours.

Goes that translate out of the petri dish and into the person? Apparently so. Soy intake was associated with only a 27 percentage breast cancer risk reduced by people with regular BRCA genes, but a 73 percent probability reduction in carriers of BRCA gene mutants. So, a health nutrition may be particularly important for those at high genetic likelihood. Meat consumption, for example, was linked to twice as much risk in those with BRCA mutations: 97 percentage increased risk instead of only 41 percent increased breast cancer risk in those with normal BRCA genes. So, the same dietary advice applies to those with and without BRCA mutants, but it’s more important when there’s more risk.

What about women without breast cancer genes or those who have already been diagnosed? See my video Is Soy Healthy for Breast Cancer Survivors ?.

What is in meat that may increase risk? See 😛 TAGEND

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In health, Michael Greger, M.D.

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2012: Uprooting the Leading Causes of Death 2013: More Than an Apple a Day 2014: From Table to Able: Combating Disabling Diseases with Food 2015: Food as Medicine: Preventing and Treating the Most Dreaded Diseases with Diet 2016: How Not To Die: The Role of Diet in Preventing, Arresting, and Reversing Our Top 15 Killers 2019: Evidence-Based Weight Loss

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