Simparica vs. Frontline Plus: Which Flea Fighter Hides the Shocking Truth Your Vet Isn’t Telling You?

Similarities & Differences

Here are the key similarities and differences between Simparica and Frontline Plus.

Similarities:

• Both Simparica and Frontline Plus are indicated to treat and prevent flea infestations.
• Each of them is effective against tick infestations caused by lone star ticks, black-legged ticks, American dog ticks and brown dog ticks.
• Both treatments kill ticks that may transmit Lyme disease.
• Both of them are designed for monthly administration.

Differences:

• While Simparica is an oral chew, Frontline Plus is a topical treatment.
• Simparica is formulated to treat and control Gulf Coast ticks and Asian longhorned ticks. Frontline Plus is not known to be effective against these tick species.
• Frontline Plus helps eliminate chewing lice and sarcoptic mange infestations. But Simparica doesn’t.
• Simparica is designed for dogs and puppies from 6 months of age, weighing at least 2.8 lbs. Frontline Plus, on the other hand, is suitable for canines from 8 weeks of age, weighing at least 5 lbs.
• While Simparica is formulated using sarolaner as its active ingredient, Frontline Plus features fipronil and (S)-methoprene as its active ingredients.
• The safe use of Simparica has not been evaluated in breeding, pregnant and lactating dogs. However, Frontline Plus is approved for use in breeding, pregnant and lactating queens.

Comparative Analysis:

Let’s take a look at a detailed comparison of the key features of Simparica and Frontline Plus

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