According to a 2023 meta-analysis on the effects of creatine supplementation combined with resistance training, this protocol can promote “a small increase in the direct measures of skeletal muscle hypertrophy in both the upper and lower body.”
Duru says for maximum muscle-building results, creatine loading can help. “The first time you take creatine, take around 20 to 25 grams of creatine every day for up to a week, broken up into 5-gram servings across the day. Then drop to the recommended 3 to 5 grams the day after this.”
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