The biggest AI breakthrough in medicine & drug discovery
MAMMAL biology foundation model that understands genes, proteins, small molecules. Beats AlphaFold 3! #ai #ainews #science #agi #singularity Thanks to our sponsor Runway. Try Runway Agent today https://runwayml.com/aisearch-agent
Full paper: https://www.nature.com/articles/s44386-026-00047-4
0:00 MAMMAL intro
0:38 Problems with drug design
1:36 How biology works
3:23 How drug design works
5:24 Why modern tech fails
6:47 How MAMMAL works
10:10 How good is it
10:59 Predicting drug toxicity
13:48 Runway Agent
15:19 Labelling cells based on gene activity
16:05 New cancer drug discovery
20:19 Implications for drug repurposing
21:16 Antibodies
22:17 MAMMAL vs Alphafold
23:29 Why Alphafold failed
26:05 Designing new drugs
27:27 Generating antibody fingers
29:29 Implications for medicine
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Here’s my equipment, in case you’re wondering:
Lenovo Thinkbook: https://amzn.to/4jWeKwH
Dell Precision 5690: https://www.dell.com/en-us/dt/ai-technologies/index.htm?utm_source=AISearchTools&utm_medium=youtube&utm_campaign=precisionai#tab0=0
GPU: Nvidia RTX 5000 Ada https://nvda.ws/3zfqGqS
Mic: Shure SM7B https://amzn.to/3DErjt1
Audio interface: Scarlett Solo https://amzn.to/3qELMeu
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